3 Nov 2013 - 3:45pm to 4:30pm
Matthew Breen knows the source of the cancers common in purebred dogs: people. As we bred dogs for behavioral and appearance traits, humans unwittingly selected for susceptibility to maladies including retinal atrophy, hip dysplasia and certain cancers. But genomic studies have revealed a silver lining: Research on these inbred populations can radically accelerate progress on cancers shared by humans and their loyal companions. By looking at 150 dogs with lymphoma, Breen and colleagues identified a genetic signature that predicts how long a dog will respond to chemotherapy.